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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1973 1
1974 2
1975 5
1976 7
1977 2
1978 5
1979 9
1980 10
1981 16
1982 6
1983 9
1984 14
1985 13
1986 12
1987 20
1988 9
1989 10
1990 7
1991 21
1992 12
1993 10
1994 19
1995 24
1996 14
1997 15
1998 24
1999 12
2000 18
2001 17
2002 20
2003 21
2004 32
2005 31
2006 31
2007 36
2008 26
2009 31
2010 36
2011 42
2012 32
2013 37
2014 35
2015 51
2016 37
2017 36
2018 49
2019 38
2020 28
2021 27
2022 27
2023 16
2024 7

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966 results

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Page 1
Effect of cholesterol on the lactosylceramide domains in phospholipid bilayers.
Hanashima S, Ikeda R, Matsubara Y, Yasuda T, Tsuchikawa H, Slotte JP, Murata M. Hanashima S, et al. Biophys J. 2022 Apr 5;121(7):1143-1155. doi: 10.1016/j.bpj.2022.02.037. Epub 2022 Feb 23. Biophys J. 2022. PMID: 35218738 Free PMC article.
Lactosylceramide (LacCer) in the plasma membranes of immune cells is an important lipid for signaling in innate immunity through the formation of LacCer-rich domains together with cholesterol (Cho). However, the properties of the LacCer domains formed in multicomponent mem …
Lactosylceramide (LacCer) in the plasma membranes of immune cells is an important lipid for signaling in innate immunity through the formati …
Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes.
Chen T, Ghosh A, Enderlein J. Chen T, et al. Nano Lett. 2023 Mar 22;23(6):2421-2426. doi: 10.1021/acs.nanolett.2c04635. Epub 2023 Jan 27. Nano Lett. 2023. PMID: 36706024 Free PMC article.
In this study, we use GIET to measure the cholesterol-induced subtle changes of membrane thickness at the nanoscale. We quantify membrane thickness variations in supported lipid bilayers (SLBs) as a function of lipid composition and increasing cholesterol …
In this study, we use GIET to measure the cholesterol-induced subtle changes of membrane thickness at the nanoscale. We quanti …
Direct Observation of Cholesterol Dimers and Tetramers in Lipid Bilayers.
Elkins MR, Bandara A, Pantelopulos GA, Straub JE, Hong M. Elkins MR, et al. J Phys Chem B. 2021 Feb 25;125(7):1825-1837. doi: 10.1021/acs.jpcb.0c10631. Epub 2021 Feb 9. J Phys Chem B. 2021. PMID: 33560844 Free PMC article.
Here, we combine solid-state nuclear magnetic resonance (NMR) spectroscopy with all-atom molecular dynamics simulations to determine the oligomeric structure of cholesterol in phospholipid bilayers. Two-dimensional (13)C-(13)C correlation spectra of di …
Here, we combine solid-state nuclear magnetic resonance (NMR) spectroscopy with all-atom molecular dynamics simulations to determine the oli …
Diosgenin-induced physicochemical effects on phospholipid bilayers in comparison with cholesterol.
Ondevilla JC, Hanashima S, Mukogawa A, Umegawa Y, Murata M. Ondevilla JC, et al. Bioorg Med Chem Lett. 2021 Mar 15;36:127816. doi: 10.1016/j.bmcl.2021.127816. Epub 2021 Jan 29. Bioorg Med Chem Lett. 2021. PMID: 33516912
Diosgenin (DGN), which is a sterol occurring in plants of the Dioscorea family, has attracted increasing attention for its various pharmacological activities. DGN has a structural similarity to cholesterol (Cho). In this study we investigated the effects of t …
Diosgenin (DGN), which is a sterol occurring in plants of the Dioscorea family, has attracted increasing attention for its various pharmacol …
Spatially Resolving the Condensing Effect of Cholesterol in Lipid Bilayers.
Leeb F, Maibaum L. Leeb F, et al. Biophys J. 2018 Dec 4;115(11):2179-2188. doi: 10.1016/j.bpj.2018.10.024. Epub 2018 Nov 2. Biophys J. 2018. PMID: 30447996 Free PMC article.
We study the effect of cholesterol on the structure of dipalmitoylphosphatidylcholine phospholipid bilayers. ...We also observe a tendency of phospholipids to orient their polar headgroups toward the cholesterol, which provides add …
We study the effect of cholesterol on the structure of dipalmitoylphosphatidylcholine phospholipid bilayers …
Cholesterol's location in lipid bilayers.
Marquardt D, Kučerka N, Wassall SR, Harroun TA, Katsaras J. Marquardt D, et al. Chem Phys Lipids. 2016 Sep;199:17-25. doi: 10.1016/j.chemphyslip.2016.04.001. Epub 2016 Apr 4. Chem Phys Lipids. 2016. PMID: 27056099 Review.
Cholesterol's location in lipid bilayers has been studied extensively, and it has been shown - at least in some bilayers - to align differently from its canonical upright orientation, where its hydroxyl group is in the vicinity of the lipid-water inter …
Cholesterol's location in lipid bilayers has been studied extensively, and it has been shown - at least in some bila …
The aggregation of striped nanoparticles in mixed phospholipid bilayers.
Noh SY, Nash A, Notman R. Noh SY, et al. Nanoscale. 2020 Feb 27;12(8):4868-4881. doi: 10.1039/c9nr07106g. Nanoscale. 2020. PMID: 31916561
We use coarse-grained computational models to investigate the structural properties of mixed phospholipid bilayers in the presence of ligand-functionalized nanoparticles. ...This study highlights the need for considering the complexity of realistic …
We use coarse-grained computational models to investigate the structural properties of mixed phospholipid bilayers in t …
Cholesterol enhances surface water diffusion of phospholipid bilayers.
Cheng CY, Olijve LL, Kausik R, Han S. Cheng CY, et al. J Chem Phys. 2014 Dec 14;141(22):22D513. doi: 10.1063/1.4897539. J Chem Phys. 2014. PMID: 25494784 Free PMC article.
Elucidating the physical effect of cholesterol (Chol) on biological membranes is necessary towards rationalizing their structural and functional role in cell membranes. ...Our data reveal that the translational diffusion of local water on the surface and within the …
Elucidating the physical effect of cholesterol (Chol) on biological membranes is necessary towards rationalizing their structural …
Molecular interactions of hesperidin with DMPC/cholesterol bilayers.
Altunayar-Unsalan C, Unsalan O, Mavromoustakos T. Altunayar-Unsalan C, et al. Chem Biol Interact. 2022 Oct 1;366:110131. doi: 10.1016/j.cbi.2022.110131. Epub 2022 Aug 28. Chem Biol Interact. 2022. PMID: 36037876
Since cell membranes are complex systems, the use of model lipid bilayers is quite important for the study of their interactions with bioactive molecules. Mammalian cell membranes require cholesterol (CHOL) for their structure and function. For this re …
Since cell membranes are complex systems, the use of model lipid bilayers is quite important for the study of their interactio …
A comparison of the behavior of cholesterol, 7-dehydrocholesterol and ergosterol in phospholipid membranes.
Chen C, Tripp CP. Chen C, et al. Biochim Biophys Acta. 2012 Jul;1818(7):1673-81. doi: 10.1016/j.bbamem.2012.03.009. Biochim Biophys Acta. 2012. PMID: 22465065 Free article.
A molecular description of the effect of incorporation of cholesterol (CHOL), 7-dehydrocholesterol (7DHC) and ergosterol (ERGO) on the structure of DPPC or EggPC liposomes is provided. ...On a molecular basis, the differences in lipid packing architecture are traced …
A molecular description of the effect of incorporation of cholesterol (CHOL), 7-dehydrocholesterol (7DHC) and ergosterol (ERGO) on th …
966 results